Health

Latest Health News, Tips, Nutrition, Diet and Fitness

Latest Health News, Tips, Nutrition, Diet and Fitness


November 4, 2022

Dietary fibre inulin promotes allergy-related inflammation in lung, gut: Study


November 4, 2022

Single dose of magic mushrooms helps treat depression in some, shows trial


November 3, 2022

New Omicron sub-variants: 5 ways mild Covid infections are affecting our health


October 31, 2022

Brain fog from long Covid: Know the symptoms, effective tips to deal with it


October 31, 2022

Intermittent fasting can affect female hormones: Research


October 31, 2022

Autistic people more vulnerable to depression, anxiety during pregnancy: Study


October 26, 2022

Diwali binge: How to eat healthy, ways to get back on track post festive season


October 26, 2022

Vaping misconceptions: Are flavoured e-cigarettes safe or cause restrictive lung disease?


October 26, 2022

Tips for pregnant women to stay healthy during festive season


October 25, 2022

Omicron BQ.1 in India: Will it cause fresh wave? Know symptoms, possibility of fresh wave, precautions


October 25, 2022

Diwali 2022 health tips: Plant-based proteins to look out for this Deepawali


October 20, 2022

Diwali workout: Set your muscles on fire with cardio and yoga combo


October 20, 2022

Diabetes: Tips to manage blood sugar levels this Diwali


October 20, 2022

Environmental chemicals that influence gastrointestinal inflammation: Research


October 19, 2022

Molecule in brain that boost body"s ability to fight Alzheimer"s, multiple sclerosis: Study


October 19, 2022

Exposure to glyphosate in pregnancy causes lower birth weights in babies: Study


October 18, 2022

Sudden cardiac arrest: Warning signs you shouldn"t ignore, know the emergency treatment, tips from cardiologist


October 18, 2022

Eye eczema: What is eyelid dermatitis, know all about triggers, warning signs


October 18, 2022

Urinary tract infection: Common causes of UTI and tips to avoid infection


October 13, 2022

World Sight Day 2022: Step-by-step easy eye exercises to improve eyesight, reduce strain


October 13, 2022

Throat cancer: Know the warning symptoms from expert and how it can be treated


October 13, 2022

Omicron’s staying power is key to mild winter as cases rise


October 13, 2022

Snack smarts: Raise your nutrition IQ (nutrient density)


October 4, 2022

Gut bacteria may contribute to HIV infection susceptibility: Study


October 4, 2022

Heart health tips: Clinical indications of echocardiogram


October 4, 2022

Protein could be used to produce life-saving antifungals: Research


October 4, 2022

8 reasons why you might have gained weight overnight


September 29, 2022

Period acne: Causes and tips to prevent it


September 29, 2022

People who delayed goals during pandemic could prevent anxiety, depression: Study


September 29, 2022

World Heart Day 2022: Why walnuts may be the top nut for a healthy heart


September 29, 2022

Diabetes: Can eating cold leftover rice improve your blood sugar levels?


September 25, 2022

World Heart Day 2022: Can screaming, losing temper trigger a heart attack? Experts answer


September 25, 2022

Diarrhea in children: From causes to symptoms, all that parents need to know


September 25, 2022

Healthy lifestyle can reduce risk of developing type 2 diabetes in women: Study


September 25, 2022

Reusable contact lens users are more likely to develop rare eye infection: Study


September 25, 2022

What is functional nutrition? Expert shares insights


September 25, 2022

Navratri fasting tips 2022: Dos and don"ts for people with diabetes during fasts


September 25, 2022

Is it heart attack or panic attack? Experts on how to differentiate


September 25, 2022

World Lung Day 2022: Yoga and Ayurveda tips to keep your lungs healthy


September 23, 2022

Coronary artery disease: Causes, symptoms, treatment, tips to stay healthier after recovering from it


September 23, 2022

Malaria spike linked to amphibian die-off: Study


September 23, 2022

Chemical mixture in skin attracts mosquitoes that spread illness


September 22, 2022

Cardiovascular diseases are linked with an increased risk of adult ADHD: Study


September 22, 2022

Valvular Heart Disease: Causes, symptoms, diagnosis and treatment


September 22, 2022

World Heart Day 2022: Tips to manage stress and keep your heart healthy


September 21, 2022

Deadly childhood diseases are increasing in Ethiopia as war hampers vaccinations


September 21, 2022

What is healthy anger and what does it look like? Expert shares insights


September 21, 2022

Seborrheic keratosis: Causes, symptoms, diagnosis and treatment of wart or mole-like benign skin tumours


September 17, 2022

Balanced meal timing may enhance brain health: Study


September 17, 2022

Is it healthy for kidney transplant recipients to limit their protein intake?


September 17, 2022

Back pain in women after 40; experts on surprising causes and prevention tips


September 16, 2022

Alcohol s single dose may be enough to permanently alter brain, cause addiction: Study


September 16, 2022

Teens with diabetes should be screened for depression with caution: Study


September 15, 2022

Health tips to manage your weight during festivals without stopping yourself from having delicious festive food


September 15, 2022

Must-have nutrients for breakfast, lunch and dinner; nutritionist suggests


September 15, 2022

Nutritionist Rujuta Diwekar suggests dos and don"ts for weight loss


September 13, 2022

Study finds new intranasal anti-viral treatment may block Covid-19 transmission


September 13, 2022

Centre’s food, public distribution dept to serve millet food in canteens, meetings


September 13, 2022

Move over fried snacks and incorporate these healthy alternatives in your children’s diet this festive season


September 13, 2022

Hand, foot and mouth disease in kids: Watch out for these symptoms; dos and don"ts for parents


September 13, 2022

Drinking sweetened, unsweetened coffee may lower risk of death: Study


September 12, 2022

India launches first cervical cancer vaccine; why it"s important to get jabbed


September 12, 2022

Key protein that drives rheumatoid arthritis damage identified: Study


September 12, 2022

Antibiotic usage in children could harm adult gut health: Study


September 12, 2022

Ultra-processed "gateway" foods might lead to unhealthy adolescent eating: Study


September 9, 2022

20-year-old dies of heart attack while dancing; can loud music be the reason? Expert take


September 9, 2022

Surprising foods that may trigger stomach pain


September 9, 2022

Women and men share same risk factors for cardiovascular disease: Study


September 8, 2022

Flu shot linked to lower risk of stroke: Research


September 8, 2022

Long covid"s link to suicide: Scientists warn of hidden crisis


September 7, 2022

7 signs that your stress hormones are high


September 7, 2022

Can you lose weight by consuming less oil? A nutritionist answers


September 7, 2022

Cancers in adults under 50 on rise globally, study finds


September 7, 2022

Nutritionist on dos and don"ts to manage unhealthy cravings this festival season


September 7, 2022

How OCD develops, can be treated: Study


September 7, 2022

Exposure to air pollution in first six months of life impacts infant"s gut bacteria, increases risk of allergies: Study


September 5, 2022

World’s first Covid vaccine you inhale is approved in China


September 5, 2022

Respiratory infections cause extreme stress to cells and organs: Research


September 5, 2022

Covid delirium: How Covid attacks brain; know common symptoms


September 5, 2022

World Leukemia Day 2022: Signs and symptoms of leukemia in newborn babies


September 5, 2022

Arterial stiffness increases blood pressure in adolescents through insulin resistance: Study


September 5, 2022

How artificial intelligence can be trained to detect tumour: Research


September 3, 2022

Females are more affected by air pollution than males: Study


September 3, 2022

5 ways to support your thyroid daily


September 3, 2022

This winter could bring "whole new" Covid strains: EU


September 3, 2022

Diabetes: Warning signs that your blood sugar is out of control


September 3, 2022

Why individual attempts to improve concentration don"t quite work


September 3, 2022

What is fermented rice; know its benefits from nutritionist


September 3, 2022

Females are more affected by air pollution than males: Study


September 2, 2022

Shape of coronavirus affects its transmission: Study


September 2, 2022

Tea drinkers enjoy possible health benefits: Study


September 2, 2022

Overweight people are more prone to argue with their doctors: Study


August 31, 2022

High blood pressure: Best ways to consume garlic for controlling BP


August 31, 2022

Effective Ayurveda tips to manage varicose veins


August 31, 2022

Sunburn: Tips to prevent yourself from the dangerous UV rays, avoid sunburn


August 30, 2022

Long COVID in children is less common than in adults? Here"s what a new study says


August 30, 2022

Fitness tips for young athletes: Common sports injuries, their treatment and dos and don"ts to prevent them


August 29, 2022

Itchy skin after Noida twin towers demolition? Skincare tips by expert


August 29, 2022

Medicinal cannabis users are more prone to nicotine consumption than general population: Research


August 28, 2022

Addiction to news can harm one"s mental and physical health: Study


August 28, 2022

All you need to know about hyperpigmentation


August 28, 2022

Lack of sleep might lead to overweight, obesity: Study


August 28, 2022

Ayurvedic rules to consume honey: Health benefits, how to eat, dos and don ts


August 28, 2022

Cardiovascular disease risk increases if you have autoimmune disorders


August 28, 2022

Incompetent cervix can lead to premature birth or pregnancy loss. Here are its symptoms, risk factors, preventive tips


August 28, 2022

Half of the mothers of autistic children suffer from depression: Study


August 26, 2022

What is leukemia and why it happens; warning signs to watch out for


August 26, 2022

Heart attack in women: Stress to menopause; know causes and warning symptoms


August 26, 2022

Heart health at risk due to potential threats from extreme weather: Research


August 26, 2022

Change in appetite characterizes depressive disorders, new study finds


August 26, 2022

Migraine diet: 3 effective Ayurvedic tips to heal migraine pain


August 26, 2022

Easy ways to get rid of dandruff


August 24, 2022

Monsoon diet tips to keep viruses and illnesses at bay


August 24, 2022

5 amazing nutrients to support your mental health


August 24, 2022

Breastfeeding and breast cancer: Here"s all you need to know


August 24, 2022

Monkeypox vs tomato flu: Know difference in symptoms from expert


August 24, 2022

Watch out for these early signs of heart failure


August 23, 2022

Children who skip breakfast may experience psychosocial health problem: Research


August 23, 2022

Mistakes we make while healing our gut: Nutritionists suggest tips


August 23, 2022

Genetic score identifies those susceptible to sudden cardiac death


August 22, 2022

An eye test could help detect autism in children: Study


August 22, 2022

Constipation diet plan: What you need to eat from morning to night for constipation relief


August 21, 2022

Children"s eyesight: Problems and their causes, who should have their eyes examined, tips for parents


August 21, 2022

Mental health and sexual disorders go hand in hand. Here"s what can be done to boost fertility in men and women


August 20, 2022

Gum cancer, a form of oral cancer: Early signs, symptoms, stages and treatment


August 20, 2022

World Mosquito Day 2022: List of vector-borne diseases caused by mosquito bite


August 20, 2022

Calorie-free sweeteners affect microbiome and glycemic response: Study


August 20, 2022

Structure of key player in antibiotic resistance: Study


August 20, 2022

World Mosquito Day 2022: What to do post mosquito bite; tips to avoid skin infection


August 20, 2022

New insights on the duration of COVID-19 infection are revealed by a study


August 20, 2022

Women have more sex partners than men in 11 states/UTs: Survey


August 18, 2022

New functions for blood-brain barrier in neuron function and damage: Research


August 18, 2022

Pediatric kidney transplant patients fare better when organ is from live donor: Study


August 18, 2022

Covid patients at increased risk of psychiatric conditions like dementia and seizures after two years: Study


August 18, 2022

Fitness tips after 60: How to maintain healthy weight


August 18, 2022

Does smoking weed affect driving? It’s complicated


August 17, 2022

Ayurveda detox tips: Check out these healthy Ayurvedic ways to remove toxins from your body


August 17, 2022

Ayurvedic rules to eat spicy food for optimum digestion


August 17, 2022

Wonderful health benefits of eating moong beans every day


August 17, 2022

First period: Early signs; how long it lasts and healthy practices to follow


August 16, 2022

Are you at risk of diabetes? Factors that increase your chances of getting the disease


August 16, 2022

Monkeypox in kids is rare but infections can be serious


August 16, 2022

Intermittent fasting side effects: How the diet plan can affect breastfeeding mom and baby


August 16, 2022

Is dyslexia a gift? Here are some surprising benefits


August 15, 2022

Chaksu seeds: Lower blood pressure with this desi superfood; know all benefits


August 15, 2022

Why has polio been found in London, NY and Jerusalem, and how dangerous is it?


August 15, 2022

Dietary salt alternatives can reduce the risk of heart attack, stroke and death


August 14, 2022

Do you know why thinking hard makes you feel exhausted? Study reveals


August 14, 2022

How to safely release anger? Know from an expert


August 13, 2022

Belly fat: Harmful habits that are making you gain visceral fat


August 13, 2022

What is chikungunya; know the warning signs and symptoms, causes and treatment


August 13, 2022

Hair Care: 7 oils you must incorporate into your hair care routine


August 13, 2022

China"s Langya henipavirus: In a "scary family" of zoonotic disease


August 12, 2022

Vegetarian women are more likely to suffer a hip fracture than meat-eating women


August 12, 2022

Antibodies that may lead to next-gen vaccines for all Covid strains found


August 12, 2022

Mental health tips: Here"s how to add self-care to your daily routine and prevent burnout


August 12, 2022

High cholesterol: Warning signs in your eyes you shouldn"t ignore


August 12, 2022

Risk of dementia might be higher if an upper heart chamber is abnormal


August 12, 2022

COVID-19 damages the brain cells? Here"s what a new study found out


August 12, 2022

monsoon rain on your health


August 11, 2022

Don’t let the monsoon rain on your health!


August 11, 2022

Fat cell development is significantly influenced by circadian clocks


August 11, 2022

Striking drop in stress hormone predicts long covid: Study


August 11, 2022

Hair care: Hair oiling mistakes that can lead to excessive hair fall


August 11, 2022

Check out "astonishing" health benefits of grapes


August 11, 2022

Raksha Bandhan 2022: Nutritionist offers mindful eating tips to avoid weight gain


August 11, 2022

5 hidden symptoms of depression you should know about


August 11, 2022

Diabetes: Walk after eating to reduce blood sugar; expert on many benefits


August 9, 2022

Vitamin D deficiency associated with chronic inflammation: Study


August 9, 2022

Eating nothing but pineapple for weight loss? Know side effects from dietician


August 9, 2022

Sudden stomach ache? 6 reasons you should know about


August 9, 2022

Elderly man undergoes surgery for removal of fungal ball from heart valve


August 9, 2022

Monkeypox vs Chickenpox: Here"s how to differentiate between them and other skin rashes or infections


August 9, 2022

Breastfeeding tips: Easy ways for new-age moms to continue giving benefits of breast milk to their baby


August 9, 2022

Fatigue, headache most common lasting symptoms months after COVID-19: Study


August 8, 2022

How mutation functions in the brain, affects anxiety and sociality: Study


August 7, 2022

Ayurveda expert on signs of health trouble in women post 30


August 7, 2022

Enjoy homemade soups this monsoon to boost immunity and lose weight


August 7, 2022

Diabetes: Breastfeeding tips for new mothers to control blood sugar levels


August 7, 2022

Identifying facial emotion expressions may alter how we view autism: Research


August 7, 2022

Ayurveda expert on easy tips to improve eye health


August 6, 2022

Cell receptor crucial for cardiovascular health: Research


August 6, 2022

Relationship among diabetes, fat and cardiovascular disease: Study


August 6, 2022

World Breastfeeding Week: Common problems faced during breastfeeding


August 5, 2022

World Breastfeeding Week: Benefits of breastfeeding for mother and child


August 5, 2022

Leucocyte Telomere Length is linked to obesity in pre-diabetic and Type 2 diabetic women


August 5, 2022

Polio fears rise in New York amid possible community spread


August 5, 2022

What causes depression? Not low serotonin levels, says new study


August 4, 2022

Diabetes: Healthy snacks to keep your sugar levels in check


August 4, 2022

Juvenile arthritis: Causes, symptoms, treatment and all you need to know about arthritis in children


August 4, 2022

Giving up toothbrush can help you get whiter teeth and less cavities: Study


August 3, 2022

Ayurvedic herbs and remedies to prevent and treat dengue


August 3, 2022

Parwal benefits: Enjoy this seasonal vegetable to keep chronic diseases at bay


August 3, 2022

Ayurveda expert on tips to manage monkeypox fever and rashes


August 3, 2022

Surgery in monsoon? Be double sure of these tips by doctors


August 2, 2022

First monkeypox death confirmed in India; common symptoms to watch out for in current outbreak


August 2, 2022

Osteoporosis: Foods to eat and avoid for preventing the condition


August 2, 2022

Diabetes: Nutritionist on healthy fats to regulate blood sugar levels


August 2, 2022

Cocoa helps to reduce blood pressure and arterial stiffness: Research


August 1, 2022

Language areas in the human brain have unique connections: Study


August 1, 2022

Monkeypox: Doctors debunk common myths


July 31, 2022

Certain opioids while on prescribed antidepressants may increase overdose risk


July 31, 2022

Plant-based meat "healthier and more sustainable than animal products": Study


July 31, 2022

Can Alzheimer"s begin in 20s? Here are signs of early onset Alzheimer"s disease


July 31, 2022

High blood pressure in children and adolescent linked to unhealthy lifestyle: Study


July 29, 2022

Mouth ulcers: Home remedies to get rid of mouth sores


July 29, 2022

How to deal with bloat


July 29, 2022

Drinking too much water can land you in serious health trouble; an expert tells you why


July 29, 2022

World ORS Day: How to make ORS at home for treating diarrhoea; health benefits of oral rehydration solution


July 29, 2022

Hepatitis in children: A possible cause for the mystery outbreak found


July 28, 2022

Processed food addiction could be related to parents" drinking patterns


July 28, 2022

Arthritis or muscular pain? How to differentiate; know from expert


July 28, 2022

Frequent naps and high blood pressure are interlinked: Study


July 28, 2022

New effective therapeutic approaches to treat tuberculosis: Research


July 28, 2022

Daily morning habits to inculcate in life: Doctors share tips


July 28, 2022

How much cholesterol should you have in a day? Know from experts


July 28, 2022

Diabetes superfoods: Fibre-rich foods you must eat for healthy blood sugar level


July 28, 2022

Japanese Encephalitis: Know symptoms, causes, treatment of the deadly mosquito-borne disease


July 26, 2022

Nutritionist on health benefits of having ginger shots on empty stomach


July 26, 2022

Vitamin B6 helps in easing depression and anxiety symptoms: Research


July 26, 2022

Constipation: Ayurveda expert on kitchen remedies for smooth bowel movement


July 26, 2022

Children prefer natural food more than processed, says a study


July 25, 2022

How cells are connected to brain tumor growth and recurrence: Research


July 25, 2022

Multiple diagnoses are the norm for mental illness: Study


July 24, 2022

World Brain Day 2022: 5 foods you must eat for better brain power


July 24, 2022

What is unexplained infertility? Here are some possible causes you need to know


July 24, 2022

Tips to take care of your heart in monsoon


July 24, 2022

Boost your immunity with amla this monsoon; know many ways of consuming it


July 24, 2022

Neem benefits: Ayurveda expert on ways to add the natural herb to daily routine


July 22, 2022

Wonderful benefits of cold shower in morning; why it works better than coffee


July 22, 2022

Vitamin D deficiency: 7 reasons your Vitamin D levels are low; signs to watch out for


July 22, 2022

Reasons why many IVF embryos fail to develop: Study


July 22, 2022

Fertility tips: Preventive measures for men and women to avoid infertility


July 22, 2022

Nutritionist suggests morning hacks to boost energy levels instantly


July 22, 2022

Stretch marks: 7 causes apart from pregnancy, effective ways to get rid of them


July 22, 2022

High blood pressure may double risk of severe Covid despite vaccination: Study


July 21, 2022

Diabetes: 5 ways to add jamun to your diet for preventing sugar spikes


July 21, 2022

5 anti-inflammatory herbs you must consume every day


July 21, 2022

White tea: Expert reveals why it is a great health companion


July 21, 2022

Marburg virus outbreak in Ghana: What you need to know


July 21, 2022

Colour blindness: Why is it more prominent in men?


July 21, 2022

What are combination vaccines? Know their benefits and side effects from expert


July 21, 2022

Inflammatory diet linked with depression: Study


July 21, 2022

Monkeypox: Person-to-person transmission, animal to human transmission, precautions and preventive measures


July 20, 2022

Diabetes: Ayurvedic remedies to prevent heart and kidney disorders in diabetics


July 20, 2022

International Chess Day 2022: Many benefits of playing chess


July 19, 2022

Are you a good candidate for in vitro fertilization? IVF experts answer


July 19, 2022

Antacids and heart diseases: Doctors explain the relationship


July 19, 2022

Post vacation, this is how Shilpa Shetty is ‘getting back to the grind


July 19, 2022

Individualised eating program helps dieters lose weight: Study


July 18, 2022

Fitness tips: 10 minutes Yoga routine for beginners


July 18, 2022

Postpartum women"s health and fitness issues and tips to work on them


July 18, 2022

Ankita Konwar merges ancient knowledge of both worlds in Egypt, works on balance


July 18, 2022

Yoga to help your skin stay younger: Say “no” to wrinkles with these exercises


July 18, 2022

Is it depression or is it anxiety? Here"s how to understand your emotions


July 18, 2022

How people curb unwanted thoughts: Study


July 18, 2022

Migraine drugs might be beneficial for weight loss: Study


July 18, 2022

Home remedies: Ayurveda expert on effective tips to treat nausea and vomiting


July 18, 2022

Why Covid-19 booster shots are essential?


July 18, 2022

5 yoga asanas for acidity: Malaika Arora’s trainer shares tips


July 18, 2022

Anti-ageing nutrients: Foods you must add to your diet to slow down aging


July 18, 2022

Monkeypox in India; experts on tips to manage symptoms


July 18, 2022

Ankita Konwar merges her love for travel and yoga ‘in the middle of the Red Sea’


July 18, 2022

5 amazing herbs to heal your gut this monsoon


July 18, 2022

Do you know lifestyle may be more important than age in determining Dementia risk?


July 16, 2022

Alia Bhatt"s trainer demonstrates asanas to combat Vertigo | Watch


July 16, 2022

Mindful meditation likely to relieve pain: Study


July 16, 2022

Vegetables to avoid in monsoon: Nutritionists share tips


July 16, 2022

Young people at higher health risk from alcohol than older adults: Study


July 16, 2022

Understanding how menstruation affects skin and hair: Dermats share insights


July 16, 2022

Monkeypox reaches India; experts offer tips to protect from the virus


July 16, 2022

5 Yoga exercises to improve memory and concentration


July 16, 2022

Turkey teeth: All about the viral trend that is leading to serious dental issues in Britons


July 16, 2022

Ways to keep Dermatitis at bay: Dermats share tips


July 16, 2022

Women can lower their rate of illness with improved diet, suggests study


July 15, 2022

Brain inflammation may link Alzheimer"s risk with sleep disturbance


July 15, 2022

Diet tips: Nutrients to consume to build your muscle health


July 14, 2022

Do you know your brain"s neurons function even in sleep?


July 14, 2022

Diabetes: 5 ways to add lemon to your diet for reducing blood sugar


July 14, 2022

Health tips to prepare your body for fertility treatments


July 13, 2022

Impact of teeth aligners on daily lifestyle: Dentists share insights


July 13, 2022

Alia Bhatt’s trainer demonstrates Vajrasana, speaks of its benefits


July 12, 2022

7 effective Ayurveda tips to keep cough and cold at bay this monsoon


July 12, 2022

Are you washing your hands too much? Expert says it can lead to this side effect


July 12, 2022

Malaika Arora to Sunny Leone, stars are obsessed with new fitness challenge: What is the trend and can you do it?


July 12, 2022

High uric acid: Ayurveda expert on easy lifestyle changes to treat the condition naturally


July 12, 2022

Alia Bhatt"s trainer demonstrates yoga asanas to boost digestive health | Watch


July 11, 2022

High cholesterol: Healthy fruits to lower bad cholesterol levels

Dietary fibre inulin promotes allergy-related inflammation in lung, gut: Study

Title description, 2022-11-04

November 4, 2022

According to researchers, a type of dietary fibre called inulin, which is used in health supplements and have certain anti-inflammatory properties, can also promote an allergy-related type of inflammation in the lung and gut, as well as other parts of the body. Researchers from Friedman Centre for Nutrition and Inflammation and Jill Roberts Institute for Inflammatory Bowel Disease at Weill Cornell Medicine and in the Boyce Thompson Institute on Cornell"s Ithaca campus published their findings in the journal Nature.

The study found that dietary inulin fiber alters the metabolism of certain gut bacteria, which in turn triggers what scientists call type 2 inflammation in the gut and lungs. This type of inflammation is thought to have evolved in mammals chiefly to defend against parasitic worm ("helminth") infections, and is also part of normal wound-healing, although its inappropriate activation underlies allergies, asthma and other inflammatory diseases.

"There"s a lot to think about here, but, in general, these findings broaden our understanding of the relationship between diet, immunity, and the normally beneficial microorganisms that constitute our microbiota and colonize our bodies," said study co-senior author Dr David Artis, director of the Friedman Center for Nutrition and Inflammation and the Michael Kors Professor of Immunology at Weill Cornell Medicine.


(Also Read | 5 wonderful drinks to beat bloating post meal)

The study"s scientific participants reflect the Friedman Center"s highly cross-collaborative research mission, drawing on expertise in bacterial genetics, biochemistry and immunology at Weill Cornell Medicine in New York City and Cornell"s Ithaca campus. Dr Chun-Jun Guo, assistant professor of immunology in medicine at Weill Cornell Medicine, and Dr Frank Schroeder, professor at the Boyce Thompson Institute and in the Department of Chemistry and Chemical Biology in the College of Arts and Sciences on Cornell"s Ithaca campus teamed up with the Artis laboratory to gain a detailed understanding of how an important dietary component affects the microbiome and the immune response. The study"s first author is Dr Mohammad Arifuzzaman, a postdoctoral researcher in the Artis laboratory.Dr. Artis is also director of the Jill Roberts Institute for Inflammatory Bowel Disease at Weill Cornell Medicine.

Small amounts of inulin are present in a wide variety of fruits and vegetables, including bananas, asparagus, and garlic. It is also frequently concentrated in commonly available high-fiber dietary supplements. Previous studies have found that inulin boosts populations of beneficial gut bacterial species which in turn boost levels of anti-inflammatory immune cells called regulatory T (Treg) cells.

In this new study, the researchers examined inulin"s effects more comprehensively. They gave mice an inulin-based, high-fiber diet for two weeks, and then analysed the many differences between these mice and mice that had been fed a diet lacking inulin. A major difference was that the inulin diet, while increasing Treg cells, also induced markedly higher levels of white blood cells called eosinophils in the gut and lungs. A high level of eosinophils is a classic sign of type 2 inflammation and is typically seen in the setting of seasonal allergies and asthma.

Ultimately the researchers found that the eosinophil response was mediated by immune cells called group 2 innate lymphoid cells (ILC2s), which were activated by elevated levels of small molecules called bile acids in the blood. The bile acid levels were elevated due to the inulin-induced growth of certain bacterial species--a group called Bacteroidetes, found in both mice and humans--which have a bile acid-metabolizing enzyme.

"We were amazed to find such a strong association between inulin supplementation and increased bile acid levels," Dr Schroeder said. "We then found that deletion of the bile acid receptor abrogates the inulin-induced inflammation, suggesting that microbiota-driven changes in bile acid metabolism underlie the effects of inulin."

"When we colonized germ-free mice (mice without microbiota) with one of these bacterial species, and then knocked out the gene for one bacterial enzyme that promotes bile acid production, the whole pathway leading from inulin to eosinophilia and allergic inflammation was blocked," Dr Guo said.

The finding that inulin promotes type 2 inflammation does not mean that this type of fiber is always "bad," the researchers said. They found that inulin did worsen allergen-induced type 2 airway inflammation in mice. But the experiments also confirmed inulin"s previously reported effect at boosting anti-inflammatory Treg cells, which may in many cases, outweigh some pro-inflammatory impact. Moreover, a type 2 immune response, which in the gut and lungs involves an increased production of tissue-protecting mucus, is not necessarily harmful in healthy people--indeed, the researchers found in their mouse experiments that the inulin-induced type 2 inflammation enhances the defense against helminth infection.

"It could be that this inulin to type-2-inflammation pathway represents an adaptive, beneficial response to endemic helminth parasite infection, though its effects in a more industrialized, helminth-free environment are more complex and harder to predict," said Dr Arifuzzaman.

The researchers now plan to use their multi-disciplinary, multi-platform approach to study systematically the immune effects of the different types of dietary fiber as well as a range of other dietary supplements in different states of health and disease. (ANI)



Single dose of magic mushrooms helps treat depression in some, shows trial

Title description, 2022-11-04

November 4, 2022

Researchers have been looking into ways to treat depression with psilocybin for years. Although some studies have shown promising results, psychiatrists aren’t prescribing magic mushrooms as an antidepressant yet. Why? In short, they haven’t found enough evidence that any positive effects they’ve observed would be translatable to the wider population. (Also read: 8 positive things to tell a person struggling with depression)

But that’s changing. New trial results published Wednesday in the New England Journal of Medicine tested the effects of psilocybin in treating depression symptoms in 233 people. The results were encouraging — a single dose of the drug reduced depressive symptoms for three weeks in nearly a third of patients with treatment-resistant depression.

Psilocybin — often referred to as "shrooms" or magic mushrooms — induce a change in perception, hallucinations and euphoria, with effects lasting up to six hours. Magic mushrooms aren’t thought to cause addiction and can be safe in moderation if correctly distinguished from other more poisonous types of mushrooms.

Side effects common

Despite the positive results, the study authors offered a sobering conclusion to the study.

Negative side effects were very common, they wrote: During the six-hour psilocybin trip, 77% of people experienced some sort of negative response to the drug, including headache, nausea and dizziness.


More worryingly, a small number of patients experienced suicidal thoughts and ideation during the trip.

However, experts cast doubt on whether it was the psilocybin itself causing the suicidal thoughts, but rather the depression itself.

One question going forward is whether people can cope with the temporary effects of the trip for the long-term benefits to depressive symptoms.

In an accompanying editorial piece, study author Bertha Madras discussed the need for therapists to identify the right patients for the treatment, and to guide a person’s experience with psilocybin.

Magic mushrooms increase brain connectivity

But how does psilocybin help treat depression? In short: Researchers aren’t quite sure yet. But they have some ideas.

According to a study published April 2022 in the journal Nature Medicine, psilocybin appears to make the brain more interconnected.

The researchers analyzed the functional magnetic resonance imaging (fMRI) of patients with depression from two previous independent clinical trials using psilocybin therapy. An fMRI is a brain scan in which the active regions of the brain can be visualized on a computer screen.

The study found that in patients undergoing psilocybin treatment for depression, brain regions appeared to be more interconnected than before the treatment. This means that parts of the brain that had previously exhibited connectivity limited within isolated regions became more connected with other regions.

Researchers say that after taking psilocybin, these patients" brain connectivity became dispersed over the whole brain.

Despite this progress, scientists are still trying to understand what it means for people who suffer from depression. It is not clear, for example, how brain connectivity impacts a person’s well-being.

Matthias Liechti, a professor of clinical pharmacology at Switzerland’s University Hospital Basel and consultant for New York-based psychedelic medicine startup MindMed, suggests this interconnectivity “could correspond to a described subjective increased flexibility and emotional relaxation.”

But researchers are far from a consensus.

Still a long trip ahead

The positive effects of psilocybin and other psychedelic drugs like LSD and ayahuasca are not limited to depression. They have also shown promising results for treating anxiety, neuropsychiatric diseases and abuse of substances like morphine and alcohol.

Many groups are calling for the endorsement of psychedelic drugs as treatment options for psychological problems. Part of this is a political response to shape access in the wake of the ‘war on drugs’.

However, many experts are calling for moderation, emphasizing the need for rigorous medical studies to ensure the drugs are effective and safe to use.

Work is underway. Nearly 200 clinical trials are currently testing the effects of medical psychedelic drugs on a range of psychological and neuropsychiatric disorders. So far, the results are encouraging, but time will tell whether they make it into clinical practice.



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